• Mcl-1 and Bcl-xL levels predict responsiveness to dual MEK/Bcl-2 inhibition in B-cell malignancies 

      Melvold, Katrine; Giliberto, Mariaserena; Karlsen, Linda; Ayuda-Duran, Maria del Pilar; Hanes, Robert; Holien, Toril; Enserink, Jorrit; Brown, Jennifer R.; Tjønnfjord, Geir Erland; Tasken, Kjetil; Skånland, Sigrid Strand (Peer reviewed; Journal article, 2021)
      Most patients with chronic lymphocytic leukemia (CLL) initially respond to targeted therapies, but eventually relapse and develop resistance. Novel treatment strategies are therefore needed to improve patient outcomes. ...